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Zhigang Qian

Research Associate Professor / Associate Researcher

  • Tel: +86-021-34207248
  • Email: zgqian@sjtu.edu.cn

Selected Publications

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    Xia XX, Qian ZG, Lee SY. 2011. Comparative proteomic and genetic analyses reveal unidentified mutations in Escherichia coli XL1-Blue and DH5α. FEMS Microbiol Lett 314(2):119-124.

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    Qian ZG, Xia XX, Lee SY. 2011. Metabolic engineering of Escherichia coli for the production of cadaverine: A five carbon diamine. Biotechnol Bioeng 108(1): 93-103.

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    Xia XX*, Qian ZG*, Ki, CS, Park, YH, Kaplan, DL, Lee SY. 2010. Native-sized recombinant spider silk protein produced in metabolically engineered Escherichia coli results in a strong fiber. Proc Natl Acad Sci USA 107(32):14059-14063. (Xia and Qian contributed equally).
    News and Views in Nature Chemical Biology (Linke WA. Biomaterials: Spider strength and stretchability. Nature Chemical Biology 6:702-703; October 2010)
    Featured by MIT Technology Review (3 August 2010)
    Featured by TCE Today (September 2010)

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    Qian ZG, Xia XX, Lee SY. 2009. Metabolic engineering of Escherichia coli for the production of putrescine: A four carbon diamine. Biotechnol Bioeng 104(4):651-662. Editors' Choice, Journal cover paper
    Wiley-Blackwell Press Release ‘Pioneering research succeeds in producing industrially vital chemical through engineered bacteria’ (27 August 2009); in numerous science news web sites
    Nature Research Highlight ‘Bacterial factories’ (Nature 461:14-15; 3 September 2009)
    BTJ-FORUM ‘Metabolic engineering of E. coli’ (Biotechnology Journal, 4:1376; October 2009)
    Top 25 Most Downloaded Articles From September-December 2009 (http://onlinelibrary.wiley.com/journal/10.1002/(ISSN)1097-0290/homepage/most_accessed_2009.htm)

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    Qian ZG, Xia XX, Choi JH, Lee SY. 2008. Proteome-based identification of fusion partner for high-level extracellular production of recombinant proteins in Escherichia coli. Biotechnol Bioeng 101(3):587-601.
    Spotlight ‘A proteome-based approach to identifying fusion partner for recombinant protein excretion’ (Biotechnology and Bioengineering DOI: 10.1002/bit.22096; 15 October 2008)

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    Xu Y, Zhao Z, Qian X, Qian Z, Tian W, Zhong J. 2006. Novel, unnatural benzo-1,2,3-thiadiazole-7-carboxylate elicitors of taxoid biosynthesis. J Agric Food Chem 54(23):8793-8798.

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    Qian ZG, Zhao ZJ, Xu Y, Qian X, Zhong JJ. 2006. Novel synthetic 2,6-dichloroisonicotinate derivatives as effective elicitors for inducing the biosynthesis of plant secondary metabolites. Appl Microbiol Biotechnol 71(2):164-167.

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    Qian ZG, Zhao ZJ, Xu Y, Qian X, Zhong JJ. 2006. Novel chemically synthesized salicylate derivative as an effective elicitor for inducing the biosynthesis of plant secondary metabolites. Biotechnol Prog 22(1):331-333.

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    Qian ZG, Zhao ZJ, Xu Y, Qian X, Zhong JJ. 2005. A novel synthetic fluoro-containing jasmonate derivative acts as a chemical inducing signal for plant secondary metabolism. Appl Microbiol Biotechnol 68(1):98-103.

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    Qian ZG, Zhao ZJ, Xu Y, Qian X, Zhong JJ. 2005. Highly efficient strategy for enhancing taxoid production by repeated elicitation with a newly synthesized jasmonate in fed-batch cultivation of Taxus chinensis cells. Biotechnol Bioeng 90(4):516-521.